Dressings Combined with Injection of Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis: A Randomized Controlled Clinical Trial

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Dressings Combined with Injection of Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis: A Randomized Controlled Clinical Trial

BACKGROUND Cutaneous leishmaniasis (CL) is a neglected infectious disease and a major health problem in several developing countries. Despite some reasonable explanation for their potential benefits, there is only trace evidence regarding the role of dressings in the treatment of CL. METHODS This randomized, assessor-blind, controlled, clinical trial was conducted in an endemic area for CL ca...

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comparison between intralesional meglumine antimoniate and combination of trichloroacetic acid 50% and intralesional meglumine antimoniate in the treatment of acute cutaneous leishmaniasis: a randomized clinical trial

background cutaneous leishmaniasis (cl) is an endemic disease in iran. pentavalent antimonials including meglumine antimoniate (ma) are still the gold standard treatment. trichloroacetic acid (tca) is used in treatment of acne scar, photodamaged skin, and some other dermatologic diseases. considering the tca potential to induce collagen synthesis and its efficacy in the treatment of papular cl ...

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omparative study of oral azithromycin and systemic meglumine antimoniate (Glucantime) in the treatment of cutaneous leishmaniasis

Background and aim: Complications and resistance to pentavalent antimonial agents in cutaneous leishmaniasis, exhibit the need for effective alternative drugs. The aim of this study was to compare the efficacy of oral azithromycin with systemic meglumine antimoniate (Glucantime) in the treatment of cutaneous leishmaniasis. Materials and Methods: Forty-seven patients with cutaneous leishmaniasis...

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Treatment of cutaneous leishmaniasis with combination of allopurinol and low dose of meglumine antimoniate

cutaneous leishmaniasis is one of the most prevalent endemic disease in Isfahan which is also hyperendemic in other parts of Iran.different treatment have been suddested for cutaneous Ieihmaniasis is glucantim and pentostam,however these drugs have significant side effects and can only be used intravenously.allopurinol is one of the oral medicines suggested for the treatment of cutaneous leishm...

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A randomized clinical trial comparing meglumine antimoniate, pentamidine and amphotericin B for the treatment of cutaneous leishmaniasis by Leishmania guyanensis.

FUNDAMENTALS American tegumentary leishmaniasis (ATL) treatment remains a challenge, since most available drugs are injectable and only a small number of comparative, randomized clinical trials have been performed to support their use. Moreover, treatment outcome may depend on the causative species of Leishmania. OBJECTIVES To evaluate and compare the efficacy and tolerability of meglumine an...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2013

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0066123